Rahman K M, Summers W A
Bangladesh Med Res Counc Bull. 1979 Jun;5(1):29-37.
The antigenic analysis of Toxocara canis a causative agent of visceral larva migrans and Ascaris suum has been carried out. Agar gel double diffusion techniques and its modifications were employed to determine whether or not crude antigens, obtained from the adult parasites: (a) contained components unique for each, (b) could be used to differentiate the parasites serologically. Adult Toxocara canis and Ascanis suum antigens used in this study were found to contain several unique antigenic components. It was shown that antisera produced in rabbits artificially immunized against adult Ascaris and Toxocara could be specifically differentiated from each other by using intragel absorption test.
对引起内脏幼虫移行症的犬弓首蛔虫和猪蛔虫进行了抗原分析。采用琼脂凝胶双向扩散技术及其改进方法,以确定从成虫寄生虫获得的粗抗原是否:(a)含有各自独特的成分,(b)可用于血清学区分寄生虫。本研究中使用的犬弓首蛔虫成虫和猪蛔虫成虫抗原被发现含有几种独特的抗原成分。结果表明,通过凝胶内吸收试验,人工免疫成年蛔虫和弓首蛔虫的家兔产生的抗血清可以相互特异性区分。