Martínez A, Asturias J A, Monteseirín J, Moreno V, García-Cubillana A, Hernández M, de la Calle A, Sánchez-Hernández C, Pérez-Formoso J L, Conde J
Hospital Virgen Macarena, Servicio de Alergia, Ville, Spain.
Allergy. 2002;57 Suppl 71:17-23. doi: 10.1034/j.1398-9995.2002.057s71017.x.
Many works have dealt with the study of the allergenic relevance of profilin from allergenic extracts, mainly derived from pollens and vegetable foods. Olive pollen extracts also contain a profilin allergen (Ole e 2). This protein has been characterized in detail, so the amino-acid sequence of three isoforms and the structural model of one of them are already known. The prevalence of Ole e 2 for olive allergenic patients has been evaluated by different in vivo and in vitro methods, and the results compared with those obtained for another pollen profilins.
许多研究致力于从变应原提取物中研究肌动蛋白结合蛋白的变应原相关性，这些提取物主要来源于花粉和植物性食物。橄榄花粉提取物中也含有一种肌动蛋白结合蛋白变应原（油橄榄花粉素2）。这种蛋白质已得到详细表征，因此三种亚型的氨基酸序列和其中一种的结构模型已为人所知。通过不同的体内和体外方法评估了油橄榄花粉素2在橄榄过敏患者中的流行情况，并将结果与其他花粉肌动蛋白结合蛋白的结果进行了比较。
