马属动物运动员中的单羧酸转运体与乳酸代谢：综述
Monocarboxylate transporters and lactate metabolism in equine athletes: a review.
作者信息
Pösö A R
机构信息
Department of Basic Veterinary Sciences, University of Helsinki, Finland.
出版信息
Acta Vet Scand. 2002;43(2):63-74. doi: 10.1186/1751-0147-43-63.
Abstract
Lactate is known as the end product of anaerobic glycolysis, a pathway that is of key importance during high intensity exercise. Instead of being a waste product lactate is now regarded as a valuable substrate that significantly contributes to the energy production of heart, non-contracting muscles and even brain. The recent cloning of monocarboxylate transporters, a conserved protein family that transports lactate through biological membranes, has given a new insight into the role of lactate in whole body metabolism. This paper reviews current literature on lactate and monocarboxylate transporters with special reference to horses.
摘要
乳酸是无氧糖酵解的终产物，无氧糖酵解在高强度运动中起着关键作用。乳酸现在不再被视为一种废物，而是一种有价值的底物，对心脏、非收缩性肌肉甚至大脑的能量产生有显著贡献。单羧酸转运蛋白是一个保守的蛋白质家族，可通过生物膜转运乳酸，最近对其进行的克隆为乳酸在全身代谢中的作用提供了新的见解。本文综述了有关乳酸和单羧酸转运蛋白的现有文献，特别提及了马。
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