Wirtz Marc, Yu Shufang, Martin Charles R
Department of Chemistry and Center for Research at the Bio/Nano Interface, University of Florida, Gainesville 32611, USA.
Analyst. 2002 Jul;127(7):871-9. doi: 10.1039/b201939f.
We have developed a new class of synthetic membranes that consist of a porous polymeric support that contains an ensemble of gold nanotubes that span the thickness of the support membrane. The support is a commercially-available microporous polycarbonate filter with cylindrical nanoscopic pores. The gold nanotubes are prepared via electroless deposition of Au onto the pore walls; i.e., the pores acts as templates for the nanotubes. We have shown that by controlling the Au deposition time, Au nanotubes that have effective inside diameters of molecular dimensions (< 1 nm) can be prepared. These membranes are a new class of molecular sieves and can be used to separate both small molecules and proteins on the basis of molecular size. In addition, the use of these membranes in new approaches to electrochemical sensing is reviewed here. In this case, a current is forced through the nanotubes, and analyte molecules present in a contacting solution phase modulate the value of this transmembrane current.
我们已经开发出一类新型合成膜，其由多孔聚合物支撑体组成，该支撑体包含贯穿支撑膜厚度的金纳米管集合。支撑体是一种具有圆柱形纳米孔的市售微孔聚碳酸酯过滤器。金纳米管通过将金化学沉积到孔壁上制备而成；也就是说，这些孔充当纳米管的模板。我们已经表明，通过控制金的沉积时间，可以制备出有效内径为分子尺寸（<1纳米）的金纳米管。这些膜是一类新型分子筛，可用于根据分子大小分离小分子和蛋白质。此外，本文还综述了这些膜在电化学传感新方法中的应用。在这种情况下，电流被迫通过纳米管，存在于接触溶液相中的分析物分子会调节该跨膜电流的值。
