Garg R K, Singh M K, Kar A M
Department of Neurology, King George's Medical College, Lucknow.
J Assoc Physicians India. 2002 May;50(5):723-5.
In children, posterior leukoencephalopathy is frequently associated with hypertensive encephalopathy, anticancer chemotherapy, treatment with immunosuppressive drugs in patients with organ transplantation, transfusion or human immunodeficiency virus infection. Posterior leukoencephalopathy in these children appears as a complicating illness and resolves once precipitating factor (e.g. cancer chemotherapy) is removed. Here we are reporting a fatal case of acute haemorrhatic leukoencephalitis in a 13 year old girl, imaging abnormalities are also suggestive of posterior leukoencephalopathy. Posterior leukoencephalopathy in our patient possibly, is a part of post-infectious haemorrhagic leukoencephalitis, rather than because of ischaemia or cerebral oedema secondary either to abrupt increase in blood pressure or following administration of immunosuppressive drugs.
在儿童中,后部白质脑病常与高血压脑病、抗癌化疗、器官移植患者使用免疫抑制药物治疗、输血或人类免疫缺陷病毒感染有关。这些儿童的后部白质脑病表现为一种并发症,一旦去除诱发因素(如癌症化疗)即可缓解。在此,我们报告一名13岁女孩患急性出血性白质脑炎的致死病例,影像学异常也提示后部白质脑病。我们患者的后部白质脑病可能是感染后出血性白质脑炎的一部分,而非由血压突然升高或使用免疫抑制药物继发的缺血或脑水肿所致。