Tomokiyo Makoto, Nishihara Kiyoshi, Nakazawa Kazutomo
Department of Neurosurgery, Kouseikai Takeda Hospital, Higashiiru, Nishinotoin Shiokoujidori, Shimogyou-ku, Kyoto-city, Kyoto 600-8558, Japan.
No Shinkei Geka. 2002 Aug;30(8):847-51.
Cerebrospinal fluid (CSF) leakage has recently been documented in most patients, as the main cause of spontaneous intracranial hypotension (SIH). No cases of SIH accompanying an episode of subarachnoid hemorrhage (SAH) has yet been reported and, to the best of our knowledge, this is the first report of a patient, who developed SAH during his clinical course of SIH. SAH was cured completely by surgical intervention. A 57-year-old man, with a history of a sustained postural headache, suffered the sudden onset of severe nuchal pain. SAH in the basal cistern, together with the finding of bilateral subdural fluid retention were verified by CT. Angiogram showed no vascular abnormalities of cerebral or cervical vessels. Gd-enhanced Magnetic Resonance Imaging (MRI) disclosed diffuse meningeal enhancement. RI cisternogram and CT-myelogram (CTM) suggested that the region of CSF leakage should be in the retrospinal area at the level of C1-2. Because orthostatic headache failed to resolve even with 3 weeks of bed rest, surgical intervention was successfully carried out to seal the site of CSF leakage with the use of a fascia and fibrin glue. We have speculated that the etiology of SAH might have been a secondary rupture of congestive intracranial veins, such as basilar plexus or bridging veins, induced by a decrease of intracranial CSF pressure.
最近已证实,脑脊液(CSF)漏是大多数患者自发性颅内低压(SIH)的主要原因。尚未有蛛网膜下腔出血(SAH)发作伴发SIH的病例报道,据我们所知,这是首例在SIH临床过程中发生SAH的患者报告。SAH通过手术干预完全治愈。一名57岁男性,有持续性体位性头痛病史,突然出现严重的颈部疼痛。CT证实基底池SAH以及双侧硬膜下积液。血管造影显示脑或颈部血管无血管异常。钆增强磁共振成像(MRI)显示弥漫性脑膜强化。放射性脑池造影和CT脊髓造影(CTM)提示CSF漏出区域应在C1-2水平的脊柱后区域。由于即使卧床休息3周,直立性头痛仍未缓解,因此成功进行了手术干预,使用筋膜和纤维蛋白胶封闭CSF漏出部位。我们推测SAH的病因可能是颅内脑脊液压力降低引起的充血性颅内静脉(如基底丛或桥静脉)继发性破裂。