Tokumura M, Yoshiba S, Kojima Y, Nanri S
Health Center, Keio University, 4-1-1 Hiyoshi Kouhoku-ku, Yokohama, Kanagawa, 223-0061 Japan.
Pediatr Cardiol. 2002 Sep-Oct;23(5):496-501. doi: 10.1007/s00246-001-0070-7.
No studies of cardiorespiratory response to brief, sudden, strenuous exercise in patients after tetralogy of Fallot (TOF) repair have been reported. We investigated the exercise capacity of TOF patients using a ten-second pedaling test designed to study cardiorespiratory responsiveness to brief, sudden, strenuous exercise. We assessed exercise capacity using a ten-second pedaling test (ten seconds maximal of voluntary cranking as fast as possible against an ergometer's inertial resistance), coupled with a conventional ramp-type progressive exercise test at a constant rate to the limit of tolerance, in eight male postoperative TOF patients and eight male control subjects. In the ten-second pedaling test, there were no significant differences in the integrated areas of heart rate (HR) and oxygen uptake () responses between the TOF patients and controls, but there were significantly longer decreasing phase time constants of HR and responses in the TOF patients than in the controls. In the conventional exercise test, the endurance time, peak-HR, and peak- did not differ between the groups. The TOF group, with a normal exercise capacity assessed by a conventional exercise test, had an impaired cardiorespiratory response to brief, sudden, strenuous exercise assessed by a ten-second pedaling test.
尚无关于法洛四联症（TOF）修复术后患者对短暂、突发、剧烈运动的心肺反应的研究报告。我们使用一项十秒蹬踏试验来研究TOF患者的运动能力，该试验旨在研究对短暂、突发、剧烈运动的心肺反应。我们对8名男性TOF术后患者和8名男性对照受试者进行了一项十秒蹬踏试验（在测力计的惯性阻力下，尽可能快地进行十秒最大自主蹬踏），并结合一项以恒定速率进行至耐受极限的传统斜坡式渐进运动试验，以评估运动能力。在十秒蹬踏试验中，TOF患者与对照组之间心率（HR）和摄氧量（）反应的积分面积无显著差异，但TOF患者心率和反应的下降相时间常数显著长于对照组。在传统运动试验中，两组之间的耐力时间、峰值心率和峰值无差异。通过传统运动试验评估运动能力正常的TOF组，在通过十秒蹬踏试验评估时，对短暂、突发、剧烈运动的心肺反应受损。
