Fedeli G, Guarnieri C, Fussi F
Ital J Biochem. 1975 Nov-Dec;24(6):309-16.
The action of a bovine gall-bladder extract is studied on two lipolytic systems: the pancreas lipase and the plasma lipoproteinlipase. For pancreas lipase the lipolytic activity of pancreas homogenates of different species is evaluated in the presence of different quantities of gall-bladder extract. For plasma lipoproteinlipase, the enzyme is induced by injection of optimal doses of heparin associated with different quantities of gall-bladder extract and the activity is evaluated by measuring the clarifying power of the plasmas of the treated animals. The results confirm that the gall-bladder contains a factor activating the pancreas lipase and put in evidence some differences between lipase activities in different species. For plasma lipolytic activation, the action of the gall-bladder extract is particularly evident in the inductive phase of lipoproteinlipase, according to a typical process of saturation.
胰腺脂肪酶和血浆脂蛋白脂肪酶。对于胰腺脂肪酶，在不同量的胆囊提取物存在下评估不同物种胰腺匀浆的脂解活性。对于血浆脂蛋白脂肪酶，通过注射与不同量胆囊提取物相关的最佳剂量肝素诱导该酶，并通过测量处理动物血浆的澄清能力来评估活性。结果证实胆囊中含有一种激活胰腺脂肪酶的因子，并揭示了不同物种脂肪酶活性之间的一些差异。对于血浆脂解激活，根据典型的饱和过程，胆囊提取物的作用在脂蛋白脂肪酶的诱导阶段尤为明显。
