Nadler Martine A, Harrison Linda M, Stephens John A
Department of Physiology, Gower St., University College London, London WC1E 6BT, UK.
Exp Brain Res. 2002 Sep;146(1):48-53. doi: 10.1007/s00221-002-1151-4. Epub 2002 Jul 17.
Changes in cutaneomuscular reflex responses (CMRs) have been studied in relation to normal ageing in man. Multiunit surface EMG signals were recorded from right and left first dorsal interosseous (1DI) hand muscles from 23 elderly adults (mean age 71.1, range 58-88 years) and 11 young adults (mean age 25.9, range 19-31 years). Subjects (1) performed index finger abduction and (2) gripped a dowel while concomitant stimulation of the digital nerves of the index finger was delivered at x2.5 threshold for perception. The E1 spinally mediated components of the CMRs recorded from 1DI were significantly smaller in the elderly subjects compared with young subjects for both tasks. The I1 and E2 transcortical components did not show a significant change in size with age although the incidence of I1 components was significantly reduced in the elderly subjects.
已经对与人类正常衰老相关的皮肤肌肉反射反应（CMRs）变化进行了研究。从23名老年人（平均年龄71.1岁，范围58 - 88岁）和11名年轻人（平均年龄25.9岁，范围19 - 31岁）的左右第一背侧骨间肌（1DI）手部肌肉记录多单元表面肌电图信号。受试者（1）进行食指外展，（2）握住一根木钉，同时以2.5倍感觉阈值刺激食指的指神经。对于这两项任务，与年轻受试者相比，从老年人1DI记录的CMRs的E1脊髓介导成分明显较小。I1和E2经皮质成分的大小并未随年龄出现显著变化，尽管老年人中I1成分的发生率显著降低。
