Pichiecchio Anna, Uggetti Carla, Grazia Egitto Maria, Zappoli Federico
Neuroradiology Department, Istituto Neurologico IRCCS Fondazione C. Mondino via Palestro, Pavia, Italy.
Neurology. 2002 Aug 27;59(4):606-8; discussion 481. doi: 10.1212/wnl.59.4.606.
Parry-Romberg syndrome or progressive facial hemiatrophy (PFH) is a rare disease of unknown etiology characterized by atrophy of the skin and subcutaneous tissue on one side of the face. The authors present the case of a 32-year-old woman with PFH who had migraine and an intracranial aneurysm. The findings support the hypothesis that the disease could be related to a neural crest migration disorder, from which both fronto-nasal mass and cranial vessels take origin.
帕里-罗姆伯格综合征或进行性面部半侧萎缩症(PFH)是一种病因不明的罕见疾病,其特征为面部一侧的皮肤和皮下组织萎缩。作者报告了一例患有PFH且伴有偏头痛和颅内动脉瘤的32岁女性病例。这些发现支持了该疾病可能与神经嵴迁移障碍有关的假说,额鼻突和颅血管均起源于神经嵴。