Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
J Stroke Cerebrovasc Dis. 2014 Feb;23(2):393-4. doi: 10.1016/j.jstrokecerebrovasdis.2013.02.015. Epub 2013 May 8.
Our objective is to report a rare coexistence of Parry-Romberg disease and ischemic stroke. Here, we report the case of a 34-year-old woman with Parry-Romberg syndrome who developed cerebral infarction. This patient developed sudden left-sided weakness and was admitted to our hospital. Magnetic resonance imaging revealed acute cerebral infarction in the posterior limb of the right internal capsule. The patient had been diagnosed with Parry-Romberg syndrome at the age of 12, and she had a history of migraine without aura. Transesophageal echocardiography revealed a patent foramen ovale, but no atrial septal aneurysm or deep vein thrombosis was observed in the lower extremities. She was treated with 200 mg of aspirin and 10 mg of atorvastatin. Her symptoms gradually improved, and she was discharged 10 days after admission. Parry-Romberg syndrome is a rare disease of progressive hemifacial atrophy with unknown etiology. The potential risk factors for ischemic stroke in Parry-Romberg syndrome include ipsilateral cerebrovascular abnormality or migraine. In addition, patent foramen ovale was identified as a concomitant risk factor in our case.
我们的目的是报告一例 Parry-Romberg 病和缺血性卒中罕见共存的病例。本文报告了一例 34 岁女性，患有 Parry-Romberg 综合征并发生脑梗死。该患者突发左侧无力，收入我院。磁共振成像显示右侧内囊后肢急性脑梗死。该患者在 12 岁时被诊断为 Parry-Romberg 综合征，有偏头痛无先兆病史。经食管超声心动图显示卵圆孔未闭，但下肢未发现心房中隔瘤或深静脉血栓形成。给予 200mg 阿司匹林和 10mg 阿托伐他汀治疗。她的症状逐渐改善，入院后 10 天出院。Parry-Romberg 综合征是一种罕见的进行性半侧颜面萎缩症，病因不明。Parry-Romberg 综合征缺血性卒中的潜在危险因素包括同侧脑血管异常或偏头痛。此外，在我们的病例中，卵圆孔未闭被认为是一个伴随的危险因素。
