Devereaux Benedict M, Leblanc Julia Kim, Yousif Edward, Kesler Kenneth, Brooks JoAnn, Mathur Praveen, Sandler Alan, Chappo John, Lehman Glen A, Sherman Stuart, Gress Frank, Ciaccia Donato
Indiana University Medical Center, Indianapolis, Indiana 46202, USA.
Gastrointest Endosc. 2002 Sep;56(3):397-401. doi: 10.1016/s0016-5107(02)70045-x.
Mediastinal masses represent a diagnostic challenge because of their proximity to numerous critical structures, difficulty of access for tissue sampling, and myriad potential pathologic etiologies. A large, single-center experience with EUS-guided fine-needle aspiration (EUS-FNA) in the diagnosis of non-lung cancer-related mediastinal masses is presented.
An EUS database was reviewed and all cases of mediastinal mass or lymphadenopathy encountered between 1994 and 1999 were included. Final diagnoses were determined by EUS-FNA cytology and clinical follow-up.
Forty-nine patients were identified (27 women, 22 men; mean age 58.1 years, range 30-89 years). A malignant process was diagnosed in 22 cases (45%) and a benign process in 24 (49%). The EUS-FNA specimen was nondiagnostic in 3 cases (6%). An accurate diagnosis was made in 46 of the 49 patients (94%). No complication was noted.
EUS-FNA is a minimally invasive technique that facilitates detection and tissue sampling of mediastinal masses. It is a safe procedure that can be performed with the patient under conscious sedation in an outpatient setting.
纵隔肿物因其靠近众多关键结构、获取组织样本困难以及潜在病理病因众多而构成诊断挑战。本文介绍了一项关于超声内镜引导下细针穿刺抽吸术（EUS-FNA）诊断非肺癌相关纵隔肿物的大型单中心经验。
回顾超声内镜数据库，纳入1994年至1999年间遇到的所有纵隔肿物或淋巴结病病例。最终诊断通过EUS-FNA细胞学检查和临床随访确定。
共确定49例患者（27例女性，22例男性；平均年龄58.1岁，范围30-89岁）。22例（45%）诊断为恶性病变，24例（49%）诊断为良性病变。3例（6%）EUS-FNA标本诊断不明确。49例患者中的46例（94%）做出了准确诊断。未观察到并发症。
EUS-FNA是一种微创技术，有助于纵隔肿物的检测和组织取样。它是一种安全的操作，可以在门诊对患者进行清醒镇静的情况下进行。
