Li Baosen, Xin Shaojie, Xing Hanqian, Zhao Jun, Zou Zhengsheng, Zhang Bin, Chen Deyong, Mao Yuanli
The 302nd Hospital of PLA, Beijing, 100039, China.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2002 Jun;16(2):157-9.
To investigate the method and therapeutic efficacy of artificial liver support system (ALSS) in treatment of severe viral hepatitis.
A total of 83 patients including 66 with severe viral hepatitis were treated with ALSS using Baxter-550 artificial kidney and Biologic-DT system.
The levels of mean bilirubin, ALT, AST, BUN, Cr and endotoxin was significantly decreased after the treatment. Of the 66 patients?with severe viral hepatitis, 31(47.0%) had improvement in symptoms and 35 (53.0%) died or left hospital. In the control group,50(27.6%) out of the 181 had improvement in symptoms and 131(72.4%) died or left hospital.
ALSS could exert certain therapeutic effects on severe viral hepatitis.
探讨人工肝支持系统(ALSS)治疗重型病毒性肝炎的方法及疗效。
采用百特-550人工肾及生物-DT系统,对包括66例重型病毒性肝炎患者在内的83例患者进行ALSS治疗。
治疗后平均胆红素、谷丙转氨酶、谷草转氨酶、尿素氮、肌酐及内毒素水平显著下降。66例重型病毒性肝炎患者中,31例(47.0%)症状改善,35例(53.0%)死亡或出院。对照组181例中,50例(27.6%)症状改善,131例(72.4%)死亡或出院。
ALSS对重型病毒性肝炎有一定治疗作用。