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人工肝支持系统治疗重型病毒性肝炎

[Treatment of severe viral hepatitis with artificial liver support system].

作者信息

Li Baosen, Xin Shaojie, Xing Hanqian, Zhao Jun, Zou Zhengsheng, Zhang Bin, Chen Deyong, Mao Yuanli

机构信息

The 302nd Hospital of PLA, Beijing, 100039, China.

出版信息

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2002 Jun;16(2):157-9.

PMID:12196829
Abstract

BACKGROUND

To investigate the method and therapeutic efficacy of artificial liver support system (ALSS) in treatment of severe viral hepatitis.

METHODS

A total of 83 patients including 66 with severe viral hepatitis were treated with ALSS using Baxter-550 artificial kidney and Biologic-DT system.

RESULTS

The levels of mean bilirubin, ALT, AST, BUN, Cr and endotoxin was significantly decreased after the treatment. Of the 66 patients?with severe viral hepatitis, 31(47.0%) had improvement in symptoms and 35 (53.0%) died or left hospital. In the control group,50(27.6%) out of the 181 had improvement in symptoms and 131(72.4%) died or left hospital.

CONCLUSIONS

ALSS could exert certain therapeutic effects on severe viral hepatitis.

摘要

背景

探讨人工肝支持系统(ALSS)治疗重型病毒性肝炎的方法及疗效。

方法

采用百特-550人工肾及生物-DT系统,对包括66例重型病毒性肝炎患者在内的83例患者进行ALSS治疗。

结果

治疗后平均胆红素、谷丙转氨酶、谷草转氨酶、尿素氮、肌酐及内毒素水平显著下降。66例重型病毒性肝炎患者中,31例(47.0%)症状改善,35例(53.0%)死亡或出院。对照组181例中,50例(27.6%)症状改善,131例(72.4%)死亡或出院。

结论

ALSS对重型病毒性肝炎有一定治疗作用。

相似文献

1
[Treatment of severe viral hepatitis with artificial liver support system].人工肝支持系统治疗重型病毒性肝炎
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2002 Jun;16(2):157-9.
2
[Treatment of severe hepatitis with artificial liver support system and liver transplantation].[人工肝支持系统及肝移植治疗重型肝炎]
Zhonghua Gan Zang Bing Za Zhi. 2001 Aug;9(4):212-3.
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[Effect of artificial liver support system on the patients with severe hepatitis].人工肝支持系统对重型肝炎患者的影响
Hunan Yi Ke Da Xue Xue Bao. 2001 Aug 28;26(4):377-8.
4
[Observation on hybrid bioartificial liver support systems in treating chronic severe hepatitis: a study of 60 cases].[杂交生物人工肝支持系统治疗慢性重型肝炎的观察:60例研究]
Zhonghua Gan Zang Bing Za Zhi. 2006 Mar;14(3):205-9.
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Artificial liver support system in China: a review over the last 30 years.中国的人工肝支持系统:过去30年回顾
Ther Apher Dial. 2006 Apr;10(2):160-7. doi: 10.1111/j.1744-9987.2006.00358.x.
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[Study of severe hepatitis treated with a hybrid artificial liver support system].[混合人工肝支持系统治疗重型肝炎的研究]
Zhonghua Gan Zang Bing Za Zhi. 2003 Aug;11(8):458-60.
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[Primary evaluation of the therapeutic effect of non-bioartificial liver support system on severe hepatitis].非生物型人工肝支持系统治疗重型肝炎疗效的初步评估
Zhonghua Gan Zang Bing Za Zhi. 2002 Feb;10(1):64.
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[The effect of artificial support system on serum cytokine in chronic severe hepatitis].[人工支持系统对慢性重型肝炎血清细胞因子的影响]
Zhonghua Gan Zang Bing Za Zhi. 2004 May;12(5):293-5.
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[Effects evaluation of middle mode artificial liver in treatment of severe hepatitis].中模人工肝治疗重型肝炎的疗效评估
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2004 Jan;16(1):6-8.
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Effects of artificial liver support system on patients with acute or chronic liver failure.人工肝支持系统对急性或慢性肝衰竭患者的影响。
Transplant Proc. 2005 Dec;37(10):4359-64. doi: 10.1016/j.transproceed.2005.11.044.

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