Diphenylhydantoin: action of a common anticonvulsant on bursting pacemaker cells in Aplysia.
作者信息
Johnston D, Avala G F
出版信息
Science. 1975 Sep 19;189(4207):1009-11. doi: 10.1126/science.1220006.
PMID:1220006
Abstract
A commonly used anticonvulsant, diphenylhydantoin (Dilantin), decreases the bursting pacemaker activity in certain cells of Aplysia. Dilantin decreases this bursting activity whether it is endogenous to the cell or induced by a convulsant agent. The sodium-dependent negative resistance characteristic which is essential for bursting behavior is reduced in the presence of Dilantin.
摘要
相似文献
1
Diphenylhydantoin: action of a common anticonvulsant on bursting pacemaker cells in Aplysia.
Science. 1975 Sep 19;189(4207):1009-11. doi: 10.1126/science.1220006.
2
The mechanism of action of diphenylhydantoin or invertebrate neurons. I. Effects on basic membrane properties.
Brain Res. 1977 Feb;121(2):245-58. doi: 10.1016/0006-8993(77)90150-0.
3
Inositol 1,4,5-trisphosphate alters bursting pacemaker activity in Aplysia neurons: voltage-clamp analysis of effects on calcium currents.肌醇1,4,5-三磷酸改变海兔神经元的爆发式起搏活动：对钙电流影响的电压钳分析
J Neurophysiol. 1988 Jul;60(1):86-104. doi: 10.1152/jn.1988.60.1.86.
4
Voltage clamp reveals basis for calcium regulation of bursting pacemaker potentials in Aplysia neurons.电压钳技术揭示了海兔神经元中爆发性起搏电位钙调节的基础。
Brain Res. 1976 May 7;107(2):418-23. doi: 10.1016/0006-8993(76)90239-0.
5
Requirements for bursting pacemaker potential activity in molluscan neurones.软体动物神经元中爆发性起搏器电位活动的要求。
Nature. 1975 Feb 6;253(5491):450-2. doi: 10.1038/253450a0.
6
Aplysia bursting neurons as endogenous oscillators. I. Phase-response curves for pulsed inhibitory synaptic input.海兔爆发性神经元作为内源性振荡器。I. 脉冲抑制性突触输入的相位响应曲线。
J Neurophysiol. 1977 May;40(3):527-43. doi: 10.1152/jn.1977.40.3.527.
7
Membrane characteristics of bursting pacemaker neurones in Aplysia.海兔中爆发式起搏神经元的膜特性
Nat New Biol. 1972 Nov 1;240(96):29-31. doi: 10.1038/newbio240029a0.
8
Modulation of a subthreshold calcium current by the neuropeptide FMRFamide in Aplysia neuron R15.海兔神经元R15中神经肽FMRF酰胺对阈下钙电流的调制作用
J Neurophysiol. 1988 Nov;60(5):1728-38. doi: 10.1152/jn.1988.60.5.1728.
9
Different sensitivities to ethanol of three early transient voltage clamp currents of aplysia neurons.海兔神经元三种早期瞬时电压钳电流对乙醇的不同敏感性
Pflugers Arch. 1974 Apr 11;348(2):139-53. doi: 10.1007/BF00586476.
10
Effects of the anticonvulsant, trimethadione, on bursting pacemaker activity and recruitment of inhibition in the abdominal ganglion of Aplysia californica.
Comp Biochem Physiol C Comp Pharmacol. 1978;60(2):145-54. doi: 10.1016/0306-4492(78)90087-4.
引用本文的文献
1
Invertebrate neurons as a simple model to study the hyperexcitable state of epileptic disorders in single cells, monosynaptic connections, and polysynaptic circuits.无脊椎动物神经元作为一种简单模型，用于研究癫痫疾病在单细胞、单突触连接和多突触回路中的过度兴奋状态。
Biophys Rev. 2022 Mar 30;14(2):553-568. doi: 10.1007/s12551-022-00942-w. eCollection 2022 Apr.
Zotero 插件