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巴特综合征:吲哚美辛对生长的长期影响(作者译)

[Bartter's syndrome: the long term effects of indomethacin on growth (author's transl)].

作者信息

Floret D, David M, Roux A, Hage G N, Teyssier G

出版信息

Nouv Presse Med. 1979 Jan 6;8(1):17-21.

PMID:122007
Abstract

Six children with Bartter's syndrome aged 6 years 4 months to 13 years 11 months were treated with indomethacin (1.7 to 4.3 mg/kg/day) during 7 to 27 months. A catch up growth was first observed, then growth curve was parallel to the normal. A catch up weight was also observed. The osseous maturation was the faster it was more delayed. These changes were observed despite a partial correction of potassium and plasma renine activity.

摘要

6名年龄在6岁4个月至13岁11个月的巴特综合征患儿接受了吲哚美辛治疗(1.7至4.3毫克/千克/天),治疗时间为7至27个月。首先观察到追赶生长,然后生长曲线与正常曲线平行。还观察到体重追赶。骨成熟延迟越久,其进展越快。尽管钾和血浆肾素活性得到部分纠正,但仍观察到这些变化。

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