β-氨基酮定向还原为顺式或反式1,3-氨基醇衍生物。
Directed reduction of beta-amino ketones to syn or anti 1,3-amino alcohol derivatives.
作者信息
Keck Gary E, Truong Anh P
机构信息
Department of Chemistry, University of Utah, 315 South 1400 East RM 2020, Salt Lake City 84112-0850, USA.
出版信息
Org Lett. 2002 Sep 5;4(18):3131-4. doi: 10.1021/ol026456y.
Abstract
[reaction: see text] The reduction of beta-amino ketones with samarium(II) iodide has been investigated. Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.
摘要
[反应：见正文] 已对用碘化钐（II）还原β-氨基酮进行了研究。由于不同N-保护基团在选择性上存在差异，顺式或反式1,3-氨基醇均可作为主要产物获得。
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