van Keulen Harry, Macechko P Timothy, Wade Susan, Schaaf Stephanie, Wallis Peter M, Erlandsen Stanley L
Department of Biological, Geological and Environmental Sciences, Cleveland State University, 2399 Euclid Avenue, Cleveland, OH 44115, USA.
Vet Parasitol. 2002 Sep 10;108(2):97-107. doi: 10.1016/s0304-4017(02)00181-4.
Giardia lamblia which parasitize humans belong to either of two genotypes, A or B, based on specific signature sequences in the 5' end of the small subunit (16S) ribosomal RNA (rRNA) gene. These two genotypes also were found in cysts from fecal samples of animal origin such as dogs, cats, some farm animals and wild animals. In addition, trophozoites recovered from cysts obtained from environmental samples belonged to these two genotypes as well, suggesting that the G. lamblia genotypes A and B are widespread and possibly zoonotic. Trophozoites were recovered from rats and these isolates might belong to another genotype of G. lamblia. Deer mice and one dog appeared to be parasitized by genotypes of Giardia with close affinity to G. microti. This species, therefore, also consists of a genotype complex.
基于小亚基(16S)核糖体RNA(rRNA)基因5'端的特定特征序列,寄生于人类的蓝氏贾第鞭毛虫属于A或B两种基因型中的一种。在狗、猫、一些农场动物和野生动物等动物源性粪便样本的囊肿中也发现了这两种基因型。此外,从环境样本获得的囊肿中回收的滋养体也属于这两种基因型,这表明蓝氏贾第鞭毛虫A和B基因型分布广泛,可能是人畜共患病原体。从大鼠中回收了滋养体,这些分离株可能属于蓝氏贾第鞭毛虫的另一种基因型。鹿鼠和一只狗似乎被与微小贾第虫亲缘关系密切的贾第虫基因型寄生。因此,该物种也由一个基因型复合体组成。