Stuurman Jeroen, Jäggi Fabienne, Kuhlemeier Cris
Institute of Plant Sciences, University of Bern, Altenbergrain 21, CH-3013 Bern, Switzerland.
Genes Dev. 2002 Sep 1;16(17):2213-8. doi: 10.1101/gad.230702.
Plant shoot development depends on the perpetuation of a group of undifferentiated cells in the shoot apical meristem (SAM). In the Petunia mutant hairy meristem (ham), shoot meristems differentiate postembryonically as continuations of the subtending stem. HAM encodes a putative transcription factor of the GRAS family, which acts non-cell-autonomously from L3-derived tissue of lateral organ primordia and stem provasculature. HAM acts in parallel with TERMINATOR (PhWUSCHEL) and is required for continued cellular response to TERMINATOR and SHOOTMERISTEMLESS (PhSTM). This reveals a novel mechanism by which signals from differentiating tissues extrinsically control stem cell fate in the shoot apex.
植物茎尖发育依赖于茎尖分生组织(SAM)中一群未分化细胞的维持。在矮牵牛突变体多毛分生组织(ham)中,茎分生组织在胚胎后期作为下方茎的延续而分化。HAM编码一种GRAS家族的假定转录因子,它从侧生器官原基的L3衍生组织和茎原维管组织非细胞自主地发挥作用。HAM与TERMINATOR(矮牵牛WUSCHEL)协同作用,是细胞对TERMINATOR和无茎分生组织(PhSTM)持续响应所必需的。这揭示了一种新机制,通过该机制,来自分化组织的信号从外部控制茎尖干细胞的命运。