Warner J, Hains S M J, Kisilevsky B S
School of Nursing, Department of Obstetrics and Gynaecology, Queen's University Kingston, General Hospital, Kingston, Ontario K7L 3N6, Canada.
Dev Psychobiol. 2002 Sep;41(2):156-68. doi: 10.1002/dev.10062.
The relationship between maternal blood pressure (BP) and fetal behaviors as well as differential spontaneous and vibroacoustic elicited fetal behaviors were examined in hypertensive (n = 21) compared to normotensive (n = 22) women at 33 and 36 weeks gestational age (GA). Maternal BP was negatively related to GA at birth and birth weight. On average, fetuses of hypertensive women were born 2 weeks earlier (38 weeks GA) and 340 g lighter. Maternal systolic BP was negatively related to the number of spontaneous body movements observed on ultrasound scan over 20 min and the magnitude of the fetal heart rate (FHR) acceleration elicited by a vibroacoustic stimulus. At 36 weeks GA, vibroacoustic stimulation elicited differential responding with fetuses in the hypertensive compared to the normotensive group having fewer body movements, a lower magnitude of FHR acceleration, and a lack of cardiac-body movement coupled responses. These findings suggest a relationship between maternal BP and fetal behaviors and differential functional development of sensory-motor response systems which need to be characterized in the subgroups of hypertensive disorders observed during pregnancy.
在孕33周和36周时，对21名高血压孕妇和22名血压正常孕妇进行研究，以考察孕妇血压（BP）与胎儿行为之间的关系，以及自发和经震动声音刺激引发的胎儿行为差异。孕妇血压与出生时的孕周和出生体重呈负相关。平均而言，高血压孕妇的胎儿出生时孕周提前2周（38周），体重轻340克。孕妇收缩压与超声扫描20分钟内观察到的自发身体运动次数以及震动声音刺激引发的胎儿心率（FHR）加速幅度呈负相关。在孕36周时，与血压正常组相比，高血压组胎儿经震动声音刺激后的反应存在差异，身体运动较少、FHR加速幅度较低，且缺乏心脏-身体运动耦合反应。这些发现表明孕妇血压与胎儿行为之间存在关联，以及感觉运动反应系统的功能发育存在差异，这需要在孕期观察到的高血压疾病亚组中进行特征描述。
