Cowperthwaite B, Hains S M J, Kisilevsky B S
Queen's University, Kingston, ON, Canada.
Infant Behav Dev. 2007 Aug;30(3):422-30. doi: 10.1016/j.infbeh.2006.12.004. Epub 2007 Jan 12.
To determine the effects of maternal smoking on fetal spontaneous behavior and auditory processing.
38 fetuses of smoking (n=18) and non-smoking (n=20) mothers, stratified by gestational age (<37, >or=37 weeks GA), were examined at least 1h following smoking. Observations included spontaneous fetal heart rate (FHR; 20 min) and body movements (20 min) followed by a 2 min audiotape of the mother reading a story while FHR and body movements were recorded.
There were no differences in spontaneous behaviors; full-term fetuses showed a FHR acceleration and body movement during the mother's voice. A FHR response following voice offset was limited to fetuses less than 37 weeks GA of non-smoking mothers.
Fetuses less than 37 weeks GA of mothers who smoke throughout pregnancy have a delayed onset of response to the maternal voice, a subtle difference which may have implications for later language development for prematurely born infants which needs further investigation.
确定母亲吸烟对胎儿自发行为和听觉处理的影响。
将38名吸烟母亲（n = 18）和非吸烟母亲（n = 20）的胎儿按孕周（<37周、≥37周）分层，在吸烟后至少1小时进行检查。观察指标包括胎儿自发心率（FHR；20分钟）和身体运动（20分钟），随后播放一段2分钟母亲朗读故事的录音带，同时记录FHR和身体运动情况。
自发行为方面无差异；足月胎儿在听到母亲声音时FHR加速且身体运动。声音停止后的FHR反应仅限于孕周小于37周的非吸烟母亲的胎儿。
整个孕期吸烟母亲的孕周小于37周的胎儿对母亲声音的反应起始延迟，这一细微差异可能对早产婴儿日后的语言发育有影响，需要进一步研究。
