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[暴发性肝炎后病程良好的慢性活动性肝炎]

[Chronic active hepatitis with a favorable course, after fulminant hepatitis].

作者信息

Hermier M, Paliard P, Bouvier R, Trépo C, Chevallier P, Bellon G

出版信息

Arch Fr Pediatr. 1979 Nov;36(9):865-72.

PMID:122140
Abstract

The case reported here is that of a girl with presumably viral non A, non B, acute hepatitis with a very unusual course. Fulminant hepatitis with submassive and bridging hepatic necrosis and a 17-day coma began during the 7th week of evolution. Prolonged chronic active hepatitis followed. Treatment was initiated 6 months after the beginning of the affection and was maintained for more than 2 years, with an apparent cure persisting after follow-up period of 6 months; fibrous scars were the only abnormalities demonstrable on histologic examination of liver biopsy. It is possible that such type of fulminant hepatitis with unusual course will become more frequent, as survival of the initial acute episode increase.

摘要

本文报告的病例是一名患可能为病毒性非甲非乙型急性肝炎的女孩,其病程非常特殊。在病程第7周时出现暴发性肝炎,伴有亚大块和桥接性肝坏死以及长达17天的昏迷。随后是迁延不愈的慢性活动性肝炎。在疾病开始6个月后开始治疗,并持续了2年多,随访6个月后仍有明显治愈迹象;肝活检组织学检查显示仅有的异常为纤维瘢痕。随着最初急性发作存活者的增多,这种病程异常的暴发性肝炎可能会变得更为常见。

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