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[酒精性肝硬化患者的下丘脑-垂体-性腺轴]

[Hypothalamic-hypophyseal-gonadal axis in patients with liver cirrhosis of alcoholic origin].

作者信息

Rallo R, Fermoso J, Ramos F, Sarmiento E, Crespo J, Marañón A

出版信息

Prensa Med Mex. 1979 Jul-Aug;44(7-8):145-51.

PMID:122169
Abstract

Plasma levels of testosterone, 17-beta-oestradiol (E2), follicle stimulating hormone (FSH) and luteinizing hormone were estimated in 19 males with alcoholic cirrhosis and in 10 healthy age matched controls in basal conditions and after administration of clomiphene citrate. The gonadal hormone response is normal in the cirrhotic group after stimulation with clomiphene citrate, suggesting a normal functional reserve of the gonad of the cirrhotic patients. It is emphasized the direct damage that the alcohol produces in the Leydig cell.

摘要

在基础状态下以及给予枸橼酸氯米芬后,对19例酒精性肝硬化男性患者和10名年龄匹配的健康对照者的血浆睾酮、17-β-雌二醇(E2)、促卵泡激素(FSH)和黄体生成素水平进行了评估。在给予枸橼酸氯米芬刺激后,肝硬化组的性腺激素反应正常,提示肝硬化患者性腺的功能储备正常。强调了酒精对睾丸间质细胞产生的直接损害。

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1
[Hypothalamic-hypophyseal-gonadal axis in patients with liver cirrhosis of alcoholic origin].[酒精性肝硬化患者的下丘脑-垂体-性腺轴]
Prensa Med Mex. 1979 Jul-Aug;44(7-8):145-51.
2
[Hypothalamic-hypophyseal-gonadal axis in chronic alcoholic patients].[慢性酒精中毒患者的下丘脑 - 垂体 - 性腺轴]
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A study of the endocrine manifestations of hepatic cirrhosis.肝硬化内分泌表现的研究。
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