Pérez-Calvo Juan, Lasierra Pilar, Moros Manuel, Iñigo Pablo
Department of Internal Medicine, Hospital Clínico Universitario Lozano Blesa, Avda. San Juan Bosco 15, E-50009 Zaragoza, Spain.
Nephron. 2002 Oct;92(2):459-62. doi: 10.1159/000063289.
Chronic hepatitis C virus (HCV) has been associated with several extrahepatic diseases, such as membranoproliferative glomerulonephritis (MPGN). alpha-Interferon is currently the treatment of choice for this association. When this therapy fails clinicians face a difficult challenge due to the lack of useful information in these particularly difficult patients. We report the case of a severe nephrotic syndrome due to MPGN associated HCV infection, in which a triple association--interferon plus ribavirin and cyclophosphamide--was needed to control the disease.
