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一株猫杯状病毒对家猫幼崽的致病性

Pathogenicity of a strain of feline calicivirus for domestic kittens.

作者信息

Love D N

出版信息

Aust Vet J. 1975 Dec;51(12):541-6. doi: 10.1111/j.1751-0813.1975.tb09376.x.

DOI:10.1111/j.1751-0813.1975.tb09376.x
PMID:1222003
Abstract

A strain of feline calicivirus, isolated from a cheetah exhibiting ulcerative glossitis and conjunctivitis, was administered by aerosol to 4 domestic cats and by contact to a fifth cat. Despite the limited number of animals available for the experiment, the pathogenicity of the virus strain for domestic cats was established. In aerosol-infected animals, clinical signs were referable to infection of both upper and lower respiratory tracts. The virus produced an interstitial pneumonia which, early in infection, was uncomplicated by secondary bronchopneumonia. The in-contact cat exhibited clinical signs referable to infection of the oral cavity only and no lesions were noted in the lower respiratory tract at autopsy. Ulcerative glossitis was a feature of the disease in aerosol-infected and in-contact cats. The virus was isolated from the pharynx of all cats for up to 21 days after infection and from the tonsils at autopsy. The tonsils were considered to be a probable site of multiplication of virus in "carrier" cats.

摘要

从一只患有溃疡性舌炎和结膜炎的猎豹身上分离出的一株猫杯状病毒,通过气溶胶方式接种给4只家猫,并通过接触方式感染了第5只猫。尽管可用于实验的动物数量有限,但该病毒株对家猫的致病性得以确定。在气溶胶感染的动物中,临床症状归因于上、下呼吸道感染。病毒引发了间质性肺炎,在感染早期,未并发继发性支气管肺炎。接触感染的猫仅表现出归因于口腔感染的临床症状,尸检时在下呼吸道未发现病变。溃疡性舌炎是气溶胶感染和接触感染猫的疾病特征。感染后长达21天,所有猫的咽部均可分离到病毒,尸检时扁桃体也可分离到病毒。扁桃体被认为是“携带”病毒的猫体内病毒增殖的可能部位。

相似文献

1
Pathogenicity of a strain of feline calicivirus for domestic kittens.一株猫杯状病毒对家猫幼崽的致病性
Aust Vet J. 1975 Dec;51(12):541-6. doi: 10.1111/j.1751-0813.1975.tb09376.x.
2
Diseases produced by feline caliciviruses when administered to cats by aerosol or intranasal instillation.通过气溶胶或滴鼻给药方式将猫杯状病毒接种于猫后所引发的疾病。
Vet Rec. 1979 Jan 27;104(4):65-9. doi: 10.1136/vr.104.4.65.
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Lesions produced by feline picornaviruses of different virulence in pathogen-free cats.不同毒力的猫细小核糖核酸病毒在无特定病原体猫中产生的病变
Vet Pathol. 1973;10(4):307-22. doi: 10.1177/030098587301000404.
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The clinical disease and patterns of excretion associated with three different strains of feline caliciviruses.与三种不同株猫杯状病毒相关的临床疾病及排泄模式。
Res Vet Sci. 1977 Jul;23(1):7-14.
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The pathology and sites of persistence associated with three different strains of feline calicivirus.与三种不同毒株猫杯状病毒相关的病理学及持续存在部位
Res Vet Sci. 1977 Jul;23(1):15-9.
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Experimentally induced feline calicivirus infection: clinical signs and lesions.实验性诱导的猫杯状病毒感染:临床症状和病变
J Am Vet Med Assoc. 1975 Mar 1;166(5):463-8.
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Feline caliciviral disease: experimental immunoprophylaxis.猫杯状病毒病:实验性免疫预防
Am J Vet Res. 1976 Mar;37(3):279-83.
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