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通过气溶胶或滴鼻给药方式将猫杯状病毒接种于猫后所引发的疾病。

Diseases produced by feline caliciviruses when administered to cats by aerosol or intranasal instillation.

作者信息

Ormerod E, McCandlish I A, Jarrett O

出版信息

Vet Rec. 1979 Jan 27;104(4):65-9. doi: 10.1136/vr.104.4.65.

DOI:10.1136/vr.104.4.65
PMID:433113
Abstract

Specific pathogen free cats were infected by two feline calicivirus isolates of different plaque type, an extra-large plaque (ep) former and a minute plaque (mp) former. A comparison was made of the disease produced when these isolates were administered by either aerosol or direct intranasal instillation. With both isolates, aerosol infection produced lesions and gave rise to virus replication throughout the respiratory tract. The effects of intranasal infection were more confined to the upper respiratory tract and oropharynx. By both routes of infection the disease produced by the mp virus was clinically and pathologically less severe than that produced by the ep virus.

摘要

无特定病原体猫被两种不同噬菌斑类型的猫杯状病毒分离株感染,一种是产生超大噬菌斑(ep)的毒株,另一种是产生微小噬菌斑(mp)的毒株。对通过气溶胶或直接鼻内滴注给予这些分离株时所产生的疾病进行了比较。对于这两种分离株,气溶胶感染都会产生病变,并导致病毒在整个呼吸道复制。鼻内感染的影响更多局限于上呼吸道和口咽。通过两种感染途径,mp病毒产生的疾病在临床和病理上都比ep病毒产生的疾病轻。

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