Woolcock J B
Aust Vet J. 1975 Dec;51(12):554-9. doi: 10.1111/j.1751-0813.1975.tb09379.x.
Using the long chain test, and in some cases the bactericidal test, to measure antibody, the development of the immune response in horses to Str. equi has been followed. Long chain indices in excess of 5.0, accompanied by strong bactericidal capacity, were recorded in serums after the full 3-dose immunisation course with a commercial vaccine. The full course elicited the most satisfactory antibody titres declined within the 12 month post-vaccination period, thus providing support for the recommendation that yearly booster doses should be administered. The immune response in horses during 2 strangles outbreaks was compared with the response following vaccination. Recovered animals showed declining antibody levels 9 weeks after infection, and the evidence does not support longevity of the immune response after natural infection. Reaction to vaccination was observed in those animals with high initial antibody titre.
通过使用长链试验，以及在某些情况下使用杀菌试验来测量抗体，追踪了马对马链球菌的免疫反应发展情况。在使用商业疫苗进行完整的3剂免疫疗程后，血清中记录到长链指数超过5.0，并伴有强大的杀菌能力。完整疗程引发了最令人满意的抗体滴度，但在接种疫苗后的12个月内滴度下降，因此支持了每年应接种加强剂量疫苗的建议。将2次马腺疫爆发期间马的免疫反应与接种疫苗后的反应进行了比较。康复的动物在感染后9周抗体水平下降，并且证据不支持自然感染后免疫反应的持久性。在那些初始抗体滴度高的动物中观察到了对疫苗接种的反应。
