Hung Dong-Zong, Wu Ming-Ling, Deng Jou-Fang, Lin-Shiau Shoei-Yn
School of Medicine, Institute of Toxicology, National Taiwan University, No 1, Section 1, Jen-Ai Road, Taipei City 100, Taiwan.
Toxicon. 2002 Sep;40(9):1291-8. doi: 10.1016/s0041-0101(02)00137-x.
Formosan Russell's viper (Daboia russelli siamensis) is the sixth most frequent cause of snakebite in Taiwan. Its venom has been thought to have both neurotoxic and hematoxic properties. This viper's snakebite is rare and thus scarcely subjected to systemic studies. In this paper, we retrospectively analyzed and described 18 cases of viper snakebite from 1987 to 1999. Like that of the Russell's viper snakebite in other South East Asian areas, varied degrees of acute renal failure, incoagulable blood with bleeding diathesis and hemolysis were the major symptoms found in the systemic envenoming patients. Systemic thrombosis seems to be the distinguishing feature in Formosan Russell's viper snakebite. Neither symptoms nor signs of neuromuscular junction blocking effects were observed, which is another difference from symptoms observed after bites of some other Russell's viper subspecies, suggesting a significant geographic variation. These findings confirmed the clinical importance of Russell's viper snakebite in Taiwan.
台湾眼镜蛇(Daboia russelli siamensis)是台湾地区蛇咬伤第六大常见病因。其毒液被认为具有神经毒性和血液毒性。这种毒蛇咬伤较为罕见,因此很少进行系统研究。在本文中,我们回顾性分析并描述了1987年至1999年间18例眼镜蛇咬伤病例。与其他东南亚地区的罗素蝰蛇咬伤情况一样,全身中毒的患者主要症状为不同程度的急性肾衰竭、血液无法凝固伴出血倾向以及溶血。全身血栓形成似乎是台湾眼镜蛇咬伤的显著特征。未观察到神经肌肉接头阻滞效应的症状或体征,这也是与其他一些罗素蝰蛇亚种咬伤后观察到的症状的另一个差异,表明存在显著的地理差异。这些发现证实了台湾地区罗素蝰蛇咬伤的临床重要性。