Hannan Wan Ibadullah Wan Abdul, Azmi Muhammad Fikri, Abas Mohd Ihsanuddin, Syed Abdul Rahim Syed Sharizman, Jeffree Mohammad Saffree, Azhar Zahir Izuan, Hayati Firdaus, Hassan Mohd Rohaizat
Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Unit of Community Medicine, Faculty of Medicine, Universiti Sultan Zainal Abidin, Terengganu, Malaysia.
Ann Med Surg (Lond). 2021 Jan 6;62:16-20. doi: 10.1016/j.amsu.2020.12.040. eCollection 2021 Feb.
This systemic review summarizes the evidence exploring the determinants of mortality due to snakebite envenomation in Asia.
The database PubMed, Web of Science and Science Direct were searched to identify the relevant literatures concerning mortality due to snakebites mortality in Asia. All the articles chosen were critically appraised for its quality using a mixed-method assessment tool by two independent reviewers with discrepancies sorted by a third person.
A total of 7 studies were included in the final analysis which was 3 cross-sectional studies, 2 case reports, 1 observation prospective study and 1 randomized control trial study. Two studies were conducted in India and two studies in Sri Lanka while one study was conducted in Taiwan, Vietnam and Nepal respectively. The cases of snakebite victims were retrieved from the year of 1987 until 2017. In total, there were 762 cases of snakebite victims recorded, with 61 of those victims succumbed to death. From the final total of 7 studies, 4 of the studies showed snakebites mortality were related to delayed treatment access and 3 studies due to suboptimal care.
Mortality and morbidity can be reduced if there is a quick access for victims to emergency medical care, rapid transfer time to hospital and receiving immediate optimal medical treatment from trained medical staff once in the hospital or dispensary.
本系统评价总结了探索亚洲蛇咬伤中毒致死决定因素的证据。
检索PubMed、科学网和科学Direct数据库,以识别有关亚洲蛇咬伤死亡率的相关文献。两名独立评审员使用混合方法评估工具对所有选定的文章进行质量严格评估,如有分歧则由第三人进行整理。
最终分析共纳入7项研究,其中3项横断面研究、2项病例报告、1项观察性前瞻性研究和1项随机对照试验研究。两项研究在印度进行,两项研究在斯里兰卡进行,而一项研究分别在台湾、越南和尼泊尔进行。蛇咬伤受害者的病例取自1987年至2017年。总共记录了762例蛇咬伤受害者病例,其中61例受害者死亡。在最终的7项研究中,4项研究表明蛇咬伤死亡率与治疗延迟有关,3项研究与护理不当有关。
如果受害者能够迅速获得紧急医疗护理、快速转送至医院并在医院或诊所接受训练有素的医务人员立即进行的最佳医疗治疗,死亡率和发病率可以降低。