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喜马拉雅东部红豆杉种群中紫杉醇及相关紫杉烷含量的变异

Variation in content of taxol and related taxanes in Eastern Himalayan populations of Taxus wallichiana.

作者信息

Mukherjee Swapna, Ghosh Biswajit, Jha Timir B, Jha Sumita

机构信息

Centre of Advanced Study, Department of Botany, University of Calcutta, Calcutta, India.

出版信息

Planta Med. 2002 Aug;68(8):757-9. doi: 10.1055/s-2002-33808.

DOI:10.1055/s-2002-33808
PMID:12221606
Abstract

Extraction and analysis of paclitaxel and other taxanes in bark, needle leaves and stem segments of male and female plants of Taxus wallichiana, representing several populations, indicate that significant variation in taxane content exists within the population. Bark accumulated maximum amount of paclitaxel in almost all plants. Populations located at higher altitude tended to accumulate more paclitaxel than lower altitude plants. Seasons in which samples were collected and plant age have also been shown to affect paclitaxel accumulation. No effects of plant sex on paclitaxel content of the plants analyzed were observed. Significant differences in baccatin-III and 10-deacetylbaccatin III content were found to exist in the trees analyzed in this study.

摘要

对代表多个种群的喜马拉雅红豆杉雌雄植株的树皮、针叶和茎段中的紫杉醇及其他紫杉烷进行提取和分析,结果表明种群内紫杉烷含量存在显著差异。几乎在所有植株中,树皮积累的紫杉醇量最多。与低海拔植株相比,高海拔种群往往积累更多的紫杉醇。采集样品的季节和植株年龄也已表明会影响紫杉醇的积累。在所分析的植株中,未观察到植株性别对紫杉醇含量有影响。在本研究分析的树木中,发现浆果赤霉素III和10 - 去乙酰浆果赤霉素III的含量存在显著差异。

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Variation in content of taxol and related taxanes in Eastern Himalayan populations of Taxus wallichiana.喜马拉雅东部红豆杉种群中紫杉醇及相关紫杉烷含量的变异
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