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[淋巴细胞酶系统的协调作用与小鼠对葡萄球菌毒素作用的抵抗力]

[Coordination of lymphocyte enzyme systems and resistance of mice to the action of staphylococcus toxin].

作者信息

Katosova L K, Katosova R K, Nartsissov R P

出版信息

Biull Eksp Biol Med. 1975 Jun;79(6):74-6.

PMID:1222255
Abstract

The activity of acid phosphatase and some dehydrogenases was studied in the blood peripheral lymphocytes of intact mice. Then this mice were given an intraperitoneal injection of LD50 of staphylococcus toxin; in 2 days 42 mice perished and 38 survived. The groups of survived and perished animals differed (the difference was statistically significant) by the extent of coordination of the enzymatic lymphocyte systems: the correlation of enzymatic indices in the survived animals was greater than in the perished ones. The data obtained are discussed from the aspect of a priori intoxication prognosis and the significance of the enzymatic coordination.

摘要

研究了完整小鼠外周血淋巴细胞中酸性磷酸酶和一些脱氢酶的活性。然后给这些小鼠腹腔注射葡萄球菌毒素的半数致死量;两天后,42只小鼠死亡,38只存活。存活和死亡动物组在酶性淋巴细胞系统的协调程度上存在差异(差异具有统计学意义):存活动物中酶指标的相关性高于死亡动物。从预先中毒预后和酶协调的意义方面对所得数据进行了讨论。

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