与原发性软脑膜黑色素瘤相关的锝-99m-六甲基丙烯胺肟摄取增加。
Increased uptake of technetium-99m-hexamethylpropyleneamine oxime related to primary leptomeningeal melanoma.
作者信息
Sagiuchi Takao, Ishii Katsumi, Utsuki Satoshi, Asano Yuuji, Tsukahara Shinya, Kan Shinichi, Fujii Kiyotaka, Hayakawa Kazushige
机构信息
Department of Radiology, Kitasato University School of Medicine, Kanagawa, Japan.
出版信息
AJNR Am J Neuroradiol. 2002 Sep;23(8):1404-6.
Abstract
We present an autopsy case of primary leptomeningeal melanoma visualized with technetium-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission CT (SPECT) of the brain. Increased uptake of Tc-99m-HMPAO coincided with leptomeningeal enhancement on MR images and with the tumor location of the autopsy findings. It was thought that Tc-99m-HMPAO could correlate closely with melanoma. Tc-99m-HMPAO SPECT clearly showed primary leptomeningeal melanoma and severe hypoperfusion induced by intracranial hypertension and tumor proliferation.
摘要
我们报告一例原发性软脑膜黑色素瘤的尸检病例，该病例通过脑的锝-99m-六甲基丙烯胺肟（Tc-99m-HMPAO）单光子发射计算机断层扫描（SPECT）得以显示。Tc-99m-HMPAO摄取增加与磁共振成像（MR）上的软脑膜强化以及尸检结果中的肿瘤位置相符。据认为，Tc-99m-HMPAO与黑色素瘤可能密切相关。Tc-99m-HMPAO SPECT清晰显示了原发性软脑膜黑色素瘤以及由颅内高压和肿瘤增殖引起的严重灌注不足。
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