Kozian Ralf
Landesklinik Brandenburg, Germany.
Psychiatr Prax. 2002 Sep;29(6):318-20. doi: 10.1055/s-2002-34039.
A potential side-effect in the treatment with olanzapine is hyperglycemia or new onset diabetes mellitus. There are possible mechanisms by which olanzapine could interfere with glucose metabolism but decreased insulin sensitivity due to weight gain is of most relevance.
使用奥氮平治疗时的一个潜在副作用是高血糖或新发糖尿病。奥氮平可能通过多种机制干扰葡萄糖代谢,但因体重增加导致胰岛素敏感性降低最为相关。