Gasanova T A
Med Parazitol (Mosk). 2002 Jan-Mar(1):3-8.
Clinical and laboratory studies were made in 2259 persons by using serological assays, including cultural and bacterioscopic assays in 1824 and 363 persons, respectively, in order to indicate Trichomonas infection among men, women, and 2-15-year-old children who had chronic inflammation of the urogenital system, as well as among children aged 2 months to 16 years who had a severe somatic disease. Parasitic cenoses of the urogenital tract were studied in women with trichomoniasis and reproductive dysfunction. Trichomonas invasion is an etiological factor of inflammatory small pelvic diseases, chronic prostatitis, reproductive dysfunction in males and females. Furthermore, trichomoniasis is an essential factor, that predisposes to recurrent viral infections: genital herpes and pointed condyloma, and substantially increases the risk of birth of babies with clinical manifestations of intrauterine infection. According to the studies, a laboratory diagnosis of trichomoniasis should be made by cultural assay due to the low sensitivity of bacterioscopy by sampling a biological material from females in the periovulatory period that corresponds to the hyperestrogenicity, which substantially increases the number of isolated cultures and characterizes the depth of integration of metabolic processes of a parasite and its host.
对2259人进行了临床和实验室研究,采用血清学检测方法,其中分别对1824人和363人进行了培养和细菌学检测,以查明患有泌尿生殖系统慢性炎症的男性、女性以及2至15岁儿童,以及患有严重躯体疾病的2个月至16岁儿童中的滴虫感染情况。对患有滴虫病和生殖功能障碍的女性的泌尿生殖道寄生虫群落进行了研究。滴虫感染是炎性盆腔疾病、慢性前列腺炎、男性和女性生殖功能障碍的病因。此外,滴虫病是一个重要因素,它易引发复发性病毒感染:生殖器疱疹和尖锐湿疣,并大幅增加出现宫内感染临床表现的婴儿出生风险。根据研究,由于在排卵期从女性采集生物材料进行细菌学检测的敏感性较低,滴虫病的实验室诊断应通过培养检测进行,这一时期雌激素水平较高,会大幅增加分离培养物的数量,并反映寄生虫及其宿主代谢过程的整合深度。