Chen R-C, Chen W-T, Liao L-Y, Cheng N-Y, Wang C-K, Tu H-Y, Wang C-S, Chen P-H
Department of Radiology, Taipei Municipal Jen-Ai Hospital, Taipei, Taiwan.
Acta Radiol. 2002 Jul;43(4):411-4. doi: 10.1080/j.1600-0455.2002.430412.x.
To compare i.v. contrast-enhanced sonography (CEUS), power Doppler sonography (PDUS) and i.a. carbon dioxide-enhanced sonography (CO2US) in assessing hepatocellular carcinoma (HCC) vascularities before and after treatment. Differences between PDUS and CEUS with the aid of CO2US were also observed.
In all, 43 patients with 67 histologically proved HCCs were examined with PDUS, CEUS, and CO2US. Among these tumors, 36 were HCCs before treatment and 31 were HCCs treated by transcatheter arterial chemoembolization or percutaneous ethanol injection or a combination of these two treatments. CO2US was used as the gold standard when comparing the PDUS and CEUS.
Of the 36 untreated HCC tumors, 20 (55.6%) were hypervascular compared with the liver parenchyma at PDUS, 28 (77.8%) at CEUS, 31 (86.1%) at the early phase of CO2US and 32 (88.9%) at the late phase of CO2US. Of the 31 post-treatment HCCs, 11 (35.5%) showed hypervascularity at PDUS, 25 (80.6%) at CEUS, 25 (80.6%) at the early phase of CO2US and 26 (83.9%) at the late phase of CO2US.
CO2US was superior to CEUS and CEUS was superior to PDUS for the detection of tumor vascularity in both untreated and treated HCCs. The duration of enhancement at CEUS was shorter than at CO2US. The ability of CO2US to detect additional small tumors was not possible with PDUS and CEUS.
比较静脉内对比增强超声（CEUS）、能量多普勒超声（PDUS）和动脉内二氧化碳增强超声（CO2US）在评估肝细胞癌（HCC）治疗前后的血管情况。同时观察PDUS和CEUS借助CO2US的差异。
总共43例经组织学证实患有67个HCC的患者接受了PDUS、CEUS和CO2US检查。在这些肿瘤中，36个为治疗前的HCC，31个为经肝动脉化疗栓塞术或经皮乙醇注射或两者联合治疗后的HCC。在比较PDUS和CEUS时，将CO2US用作金标准。
在36个未经治疗的HCC肿瘤中，与肝实质相比，PDUS显示20个（55.6%）为高血管，CEUS显示28个（77.8%），CO2US早期显示31个（86.1%），CO2US晚期显示32个（88.9%）。在31个治疗后的HCC中，PDUS显示11个（35.5%）为高血管，CEUS显示25个（80.6%），CO2US早期显示25个（80.6%），CO2US晚期显示26个（83.9%）。
对于未治疗和已治疗的HCC，CO2US在检测肿瘤血管方面优于CEUS，CEUS优于PDUS。CEUS的增强持续时间短于CO2US。PDUS和CEUS无法检测到CO2US发现额外小肿瘤的能力。
