肝母细胞瘤与低出生体重：一种趋势还是偶然观察结果？
Hepatoblastoma and low birth weight: a trend or chance observation?
作者信息
Feusner James, Plaschkes J
机构信息
Oncology, Children's Hospital Oakland, Oakland, California 94609, USA.
出版信息
Med Pediatr Oncol. 2002 Nov;39(5):508-9. doi: 10.1002/mpo.10176.
BACKGROUND
Several reports have suggested an association between prematurity and hepatoblastoma (HB).
PROCEDURE
Data were collected by questionnaires from 105 children with HB enrolled in a Children's Cancer Group (CCG) study.
RESULTS
Observed over expected rates were increased about 2- and 15+-fold for prematurity (<37 weeks at birth) and low birth weight (<1,000 g) respectively. Similar data were derived from a later CCG study of 36 HB children.
CONCLUSIONS
Early reports of a possible association between prematurity and HB have been confirmed.
背景
多项报告提示早产与肝母细胞瘤（HB）之间存在关联。
过程
通过问卷调查收集了参加儿童癌症研究组（CCG）研究的105例HB患儿的数据。
结果
早产（出生时<37周）和低出生体重（<1000克）的观察/预期率分别增加了约2倍和15倍以上。来自CCG后来一项对36例HB患儿的研究也得出了类似数据。
结论
早产与HB之间可能存在关联的早期报告得到了证实。
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