Burg G, Hirsch R D, Konz B, Braun-Falco O
J Dermatol Surg. 1975 Oct;1(3):21-4. doi: 10.1111/j.1524-4725.1975.tb00089.x.
In 72 basal-cell epitheliomas, the clinical extension and the actual extension of the defect measured by complete tumor removal by Mohs' chemosurgery were compared. Subclinical extension depends on the type of basal-cell epithelioma (primary, recurrent), on case history, location, clinical diameter, number of previous treatments and histological type. It is remarkably great in large (diameter more than 20 mm), in morphea-like basal-cell epitheliomas on the forehead, temple and scalp, especially following several previous treatments. In such cases the excision should include at least a 5-10 mm margin of "normal tissue." Present results again show that "histographic," that is, Mohs' chemosurgery is the method of choice for the treatment for these tumors.
对72例基底细胞上皮瘤患者,比较了临床扩展范围与通过莫氏化学外科手术完整切除肿瘤所测量的缺损实际扩展范围。亚临床扩展取决于基底细胞上皮瘤的类型(原发性、复发性)、病史、位置、临床直径、既往治疗次数和组织学类型。在直径大于20毫米的肿瘤、前额、颞部和头皮的硬斑病样基底细胞上皮瘤中,尤其是在经过数次既往治疗后,亚临床扩展非常明显。在这种情况下,切除范围应至少包括5 - 10毫米的“正常组织”边缘。目前的结果再次表明,“组织绘图法”,即莫氏化学外科手术是治疗这些肿瘤的首选方法。