Okamoto Hiroyuki
Department of Dermatology, Kansai Medical University.
Nihon Rinsho. 2002 Sep;60(9):1801-6.
The frequency of skin involvement of sarcoidosis is 10-30% of all cases, but the prevalence of a particular type of cutaneous lesion varies among races as well as individual cases. Cutaneous involvement is divided into specific and nonspecific categories. Specific lesions include nodules, plaques, lupus pernio, subcutaneous nodules, and other rare manifestations as well as scar infiltrates. Despite the clinical importance of scar infiltrates in the diagnosis of sarcoidosis, it is often overlooked because the lesions are usually small and asymptomatic. There is some clinical importance of cutaneous sarcoidosis; the ease in obtaining lesional samples which enables a histological diagnosis of sarcoidosis, and the association of a particular type of cutaneous lesion with other organ involvement.
结节病皮肤受累的频率在所有病例中为10% - 30%,但特定类型皮肤病变的患病率在不同种族以及个体病例之间存在差异。皮肤受累分为特异性和非特异性两类。特异性病变包括结节、斑块、冻疮样狼疮、皮下结节以及其他罕见表现,还有瘢痕浸润。尽管瘢痕浸润在结节病诊断中具有临床重要性,但因其病变通常较小且无症状,所以常被忽视。皮肤结节病具有一定临床意义,它便于获取病变样本以实现结节病的组织学诊断,并且特定类型的皮肤病变与其他器官受累相关。