Suga Y, Ogawa H
Juntendo University School of Medicine.
Nihon Rinsho. 1994 Jun;52(6):1603-7.
Sarcoidosis is characterized by formation of epithelioid-cell tubercules, without caseation, of the affected organ systems. The mediastinum, peripheral lymph nodes and eyes, in addition to the skin, are most frequently affected. Between 10% and 30% of patients with systemic sarcoidosis in Japan have skin lesions. Skin sarcoidosis is morphologically classified into three basic groups, erythema nodosum, scar sarcoidosis and skin sarcoid. Skin sarcoid is characterized by specific cutaneous lesions of sarcoidosis, and may take nodular, plaque, angiolupoid, subcutaneous and some other forms. Clinical manifestations of the cutaneous lesions are usually asymptomatic and polymorphous. Skin biopsy is, however, often highly useful for confirming a diagnosis of sarcoidosis.
结节病的特征是在受影响的器官系统中形成上皮样细胞结节，无干酪样坏死。除皮肤外，纵隔、外周淋巴结和眼睛最常受累。在日本，10%至30%的系统性结节病患者有皮肤病变。皮肤结节病在形态学上分为三个基本类型，即结节性红斑、瘢痕结节病和皮肤结节病。皮肤结节病的特征是结节病的特异性皮肤病变，可呈结节状、斑块状、血管狼疮样、皮下及其他一些形式。皮肤病变的临床表现通常无症状且多样。然而，皮肤活检对于确诊结节病往往非常有用。
