Katta Rajani
Baylor College of Medicine, Houston, Texas 77030, USA.
Am Fam Physician. 2002 Apr 15;65(8):1581-4.
Sarcoidosis is a multisystem disease that may involve almost any organ system; therefore, it results in various clinical manifestations. Cutaneous sarcoidosis occurs in up to one third of patients with systemic sarcoidosis. Recognition of cutaneous lesions is important because they provide a visible clue to the diagnosis and are an easily accessible source of tissue for histologic examination. Because lesions can exhibit many different morphologies, cutaneous sarcoidosis is known as one of the "great imitators" in dermatology. Specific manifestations include papules, plaques, lupus pernio, scar sarcoidosis, and rare morphologies such as alopecia, ulcers, hypopigmented patches, and ichthyosis. Treatment of cutaneous lesions can be frustrating. For patients with severe lesions or widespread involvement, the most effective treatment is systemic glucocorticoids.
结节病是一种多系统疾病，几乎可累及任何器官系统；因此，它会导致各种临床表现。皮肤结节病在多达三分之一的系统性结节病患者中出现。认识皮肤病变很重要，因为它们为诊断提供了明显线索，并且是易于获取的组织学检查组织来源。由于病变可呈现多种不同形态，皮肤结节病被认为是皮肤科的“伟大模仿者”之一。具体表现包括丘疹、斑块、冻疮样狼疮、瘢痕结节病，以及罕见形态如脱发、溃疡、色素减退斑和鱼鳞病。皮肤病变的治疗可能令人沮丧。对于病变严重或广泛受累的患者，最有效的治疗方法是全身使用糖皮质激素。
