Modified constraint-induced therapy after subacute stroke: a preliminary study.

OBJECTIVE

To determine the efficacy of a modified constraint-induced therapy (mCIT) administered to patients with subacute stroke.

DESIGN

Prospective, multiple-baseline, before-after, randomized clinical trial.

SETTING

Subacute outpatient clinic.

SUBJECTS

Fourteen patients with subacute stroke who exhibited learned nonuse and stable motor deficits in their affected upper limbs.

INTERVENTION

Four patients participated in half-hour, structured physical and occupational therapy sessions that emphasized affected arm use in valued functional activities, 3 times per week for 10 weeks. Their less affected upper limbs were restrained 5 days per week during 5 hours identified as times of frequent use (mCIT). Five patients received regular therapy (TR) with similar therapeutic contact time to mCIT and 5 patients received no therapy (CON).

MAIN OUTCOME MEASURES

The Fugl-Meyer Assessment of Motor Recovery (Fugl), Action Research Arm (ARA) test, and Motor Activity Log (MAL).

RESULTS

After intervention, Fugl, ARA, and MAL scores remained virtually the same for TR and CON groups; scores improved by 11.4 and 11.5points, respectively, on the Fugl and ARA for the mCIT group. Amount and quality of arm use, as measured by the MAL, also improvedfor mCIT patients (2.49 and 0.47, respectively).

CONCLUSIONS

mCIT may be an efficacious method of improving affected arm function and use in stroke patients exhibiting learned nonuse.