Claflin Edward S, Krishnan Chandramouli, Khot Sandeep P
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Department of Neurology, University of Washington, Seattle, WA, USA.
Neurohospitalist. 2015 Apr;5(2):77-88. doi: 10.1177/1941874414561023.
Although numerous treatments are available to improve cerebral perfusion after acute stroke and prevent recurrent stroke, few rehabilitation treatments have been conclusively shown to improve neurologic recovery. The majority of stroke survivors with motor impairment do not recover to their functional baseline, and there remains a need for novel neurorehabilitation treatments to minimize long-term disability, maximize quality of life, and optimize psychosocial outcomes. In recent years, several novel therapies have emerged to restore motor function after stroke, and additional investigational treatments have also shown promise. Here, we familiarize the neurohospitalist with emerging treatments for poststroke motor rehabilitation. The rehabilitation treatments covered in this review will include selective serotonin reuptake inhibitor medications, constraint-induced movement therapy, noninvasive brain stimulation, mirror therapy, and motor imagery or mental practice.
尽管有许多治疗方法可用于改善急性中风后的脑灌注并预防中风复发,但很少有康复治疗被确凿证明能改善神经功能恢复。大多数有运动障碍的中风幸存者无法恢复到其功能基线,因此仍需要新的神经康复治疗来尽量减少长期残疾、最大化生活质量并优化心理社会结局。近年来,出现了几种新的疗法来恢复中风后的运动功能,其他研究性治疗也显示出了前景。在此,我们向神经科住院医师介绍中风后运动康复的新兴治疗方法。本综述涵盖的康复治疗将包括选择性5-羟色胺再摄取抑制剂药物、强制性运动疗法、无创脑刺激、镜像疗法以及运动想象或心理练习。