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泰国彭世洛地区血液中心献血者中乙型肝炎、丙型肝炎和人类免疫缺陷病毒的血清流行率

Seroprevalence of hepatitis B, hepatitis C and human immunodeficiency virus among blood donors, Phitsanulok Regional Blood Center, Thailand.

作者信息

Luksamijarulkul Pipat, Thammata Nantaporn, Tiloklurs Mujarin

机构信息

Department of Microbiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 2002 Jun;33(2):272-9.

Abstract

Human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV) infections are important blood-borne infections in many countries including Thailand. For epidemiological surveillance and controlling these infections, a cross-sectional group of 2,167 blood donors were screened for HBsAg, antibodies to HCV and HIV by enzyme immunoassay methods. The results revealed that the prevalence of HBsAg positive among studied blood donors was 4.61%, anti-HCV was 2.90% and anti-HIV was 0.69%. When the prevalence was classified by selected socio-demographic variables, it was found that variables including age, gender, marital status and occupation were significant for HBsAg positive rate (p=0.0068, p=0.0019, p=0.0048 and p=0.0017, respectively). For anti-HCV prevalence, studied variables including educational level, occupation and domicile were significant (p<0.0001, p=0.0027, and p<0.0001, respectively), while only educational level was a significant variable for anti-HIV prevalence (p=0.0021). These findings suggest that we should present integrated information and educational programs for preventing and controlling HBV, HCV and HIV transmission among this target group.

摘要

人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)和乙型肝炎病毒(HBV)感染在包括泰国在内的许多国家都是重要的血源性感染。为了进行这些感染的流行病学监测和控制,采用酶免疫测定法对2167名献血者进行横断面筛查,检测乙肝表面抗原(HBsAg)、抗丙型肝炎病毒抗体和抗人类免疫缺陷病毒抗体。结果显示,在研究的献血者中,HBsAg阳性率为4.61%,抗HCV为2.90%,抗HIV为0.69%。当按选定的社会人口统计学变量对患病率进行分类时,发现年龄、性别、婚姻状况和职业等变量对HBsAg阳性率有显著影响(p值分别为0.0068、0.0019、0.0048和0.0017)。对于抗HCV患病率,所研究的教育水平、职业和住所等变量有显著影响(p值分别<0.0001、0.0027和<0.0001),而对于抗HIV患病率,只有教育水平是一个显著变量(p=0.0021)。这些发现表明,我们应该提供综合信息和教育项目,以预防和控制该目标群体中的HBV、HCV和HIV传播。

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