Rabhi Yayha A, Fabbro-Peray Pascale, Dauzat Michel, Montesinos Philippe, Oliva-Lauraire Marie-Claire, Lopez François-Michel, Quéré Isabelle, Gris Jean-Christophe, Brun Jean-Frédéric, Pourcelot Léandre
Laboratory of Cardio-Vascular Physiology, Faculty of Medicine, Montpellier I University, Nimes, France.
Clin Hemorheol Microcirc. 2002;27(1):27-41.
Spontaneous blood echogenicity in vein ultrasound images may be a marker for an increased erythrocyte aggregability, but a reliable quantitative evaluation method is a prerequisite for its use in clinical studies. We compared a simple scoring system of blood echogenicity intensity and pattern, with automatic image analysis.
157 femoral and popliteal vein digitized ultrasound sequences were reviewed by two independent observers who chose an image, delimited an area of interest (ROI), and graded blood echogenicity intensity and pattern, using a four class score. Each observer reviewed the images selected by the other, without and with ROI. The computer calculated first and second order parameters describing echo intensity and spatial organization.
Inter-observer reproducibility of subjective assessment was poor (Kappa<0.5), whereas the automatically calculated ROI average gray level intensity relatively to the whole image (tau(1)) effectively separated all grades of intensity. No parameter effectively separated patterns.
Tau(1) is a simple parameter for the in vivo evaluation of blood echogenicity intensity. It should be evaluated in standardized conditions for clinical hemorheology studies in correlation with in vitro erythrocyte aggregation measurements.
静脉超声图像中的自发性血液回声性可能是红细胞聚集性增加的一个标志，但可靠的定量评估方法是其用于临床研究的前提条件。我们将一种简单的血液回声强度和模式评分系统与自动图像分析进行了比较。
两名独立观察者对157个股静脉和腘静脉数字化超声序列进行了回顾，他们选择一幅图像，划定感兴趣区域（ROI），并使用四级评分对血液回声强度和模式进行分级。每位观察者对另一位观察者选择的有无ROI的图像进行回顾。计算机计算描述回声强度和空间组织的一阶和二阶参数。
主观评估的观察者间再现性较差（kappa<0.5），而相对于整个图像自动计算的ROI平均灰度强度（tau(1)）有效地分离了所有强度等级。没有参数能有效分离模式。
Tau(1)是用于体内评估血液回声强度的一个简单参数。在临床血液流变学研究中，应在标准化条件下将其与体外红细胞聚集测量相关联进行评估。
