金盐治疗后危及生命的小肠结肠炎
Life-threatening enterocolitis after gold salt therapy.
作者信息
Sckolnick B R, Katz L A, Kozower M
出版信息
J Clin Gastroenterol. 1979 Jun;1(2):145-8. doi: 10.1097/00004836-197906000-00006.
Abstract
Two patients developed life-threatening enterocolitis after receiving gold salt therapy. This disorder is attended by a mortality rate of 50% but the intestinal lesion appears to be reversible. The mechanism of the drug toxicity is not known. The course may be fulminant and recovery may occur only after many weeks. Total bowel rest, nasogastric suction, total parenteral nutrition with supplemental colloid and careful monitoring of fluid and electrolyte balance may improve survival.
摘要
两名患者在接受金盐治疗后发生了危及生命的小肠结肠炎。这种疾病的死亡率为50%，但肠道病变似乎是可逆的。药物毒性的机制尚不清楚。病程可能是暴发性的，可能要经过数周才会恢复。完全肠道休息、鼻胃管抽吸、补充胶体的全胃肠外营养以及仔细监测液体和电解质平衡可能会提高生存率。
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