与胃肠外金疗法相关的致命性肝坏死。
Fatal hepatic necrosis associated with parenteral gold therapy.
作者信息
Watkins P B, Schade R, Mills A S, Carithers R L, Van Thiel D H
机构信息
University of Pittsburgh, Department of Medicine, Pennsylvania 15261.
出版信息
Dig Dis Sci. 1988 Aug;33(8):1025-9. doi: 10.1007/BF01536001.
PMID:3134176
Abstract
Two young black male patients with seronegative rheumatoid arthritis and treated with nonsteroidal antiinflammatory agents developed fulminant hepatic necrosis following the institution of parenteral gold therapy. These cases, reported from different institutions, may represent a severe form of idiosyncratic gold hepatonecrosis. Awareness of the possible association between gold therapy and severe hepatic injury may become increasingly important as oral gold preparations become widely available.
摘要
两名患有血清阴性类风湿性关节炎且接受非甾体抗炎药治疗的年轻黑人男性患者，在接受胃肠外金疗法后发生了暴发性肝坏死。这些来自不同机构报告的病例，可能代表了一种严重的特发性金中毒性肝坏死。随着口服金制剂的广泛应用，认识到金疗法与严重肝损伤之间可能存在的关联可能变得越来越重要。
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Hepatotoxicity with aurothioglucose therapy.金硫葡萄糖治疗导致的肝毒性。
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Liver dysfunction associated with gold therapy for rheumatoid arthritis.与类风湿关节炎金疗法相关的肝功能障碍。
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