Landauer A A
Pharmacol Biochem Behav. 1975 Nov-Dec;3(6):1141-5. doi: 10.1016/0091-3057(75)90031-3.
Simple crossover studies with drugs may introduce artifactual results. Volunteers are frequently less apprehensive when tested on the second occasion and experimental medication may result in different performance measures. Empirical evidence is given to demonstrate this point and a suggestion is made as to how it can be overcome.
药物的简单交叉研究可能会产生人为的结果。志愿者在第二次测试时往往不那么担心,而且实验药物可能会导致不同的表现指标。给出了实证证据来证明这一点,并就如何克服这一点提出了建议。