抗坏血酸对实验性胆汁淤积和氨基核苷肾病中高胆固醇血症的影响（作者译）

[The effect of ascorbic acid on the hypercholesterolemia in experimental cholestasis and aminonucleoside nephrosis (author's transl)].

作者信息

Froese P, Leipnitz W, Scholz A

出版信息

Res Exp Med (Berl). 1975 Jul 14;165(2):135-40. doi: 10.1007/BF01854839.

Abstract

Hypercholesterolemia was induced in rats by experimental cholestasis and aminonucleoside nephrosis. After ascorbic acid administration the hypercholesterolemia was significantly decreased in both cases. In the case of cholestasis serum choelsterol was normal and in the case of nephrosis serum cholesterol remained above normal.

摘要

通过实验性胆汁淤积和氨基核苷肾病在大鼠中诱发高胆固醇血症。给予抗坏血酸后，两种情况下的高胆固醇血症均显著降低。在胆汁淤积的情况下，血清胆固醇正常；而在肾病的情况下，血清胆固醇仍高于正常水平。