Dubbert Patricia M, Carithers Teresa, Sumner Anne E, Barbour Krista A, Clark Bobby L, Hall John E, Crook Errol D
University of Mississippi School of Medicine, Jackson, USA.
Am J Med Sci. 2002 Sep;324(3):116-26. doi: 10.1097/00000441-200209000-00002.
Despite considerable progress in understanding disease mechanisms and risk factors, improved treatments, and public education efforts, cardiovascular disease (CVD) remains the leading cause of death in the United States. Obesity and physical inactivity, 2 important lifestyle-related risk factors for CVD, are prevalent in the southeastern United States and are becoming more prevalent in all racial groups and areas of the country. In reviewing these risk factors, we explored topics including prevalence and trends in population data; associated psychosocial and environmental factors; and some of the mechanisms through which these risk factors are thought to contribute to CVD. We identified significant, but as yet poorly understood, racial disparities in prevalence of obesity, low levels of physical activity, and correlates of these risk factors and examined important differences in the complex relationship between obesity, diabetes, and cardiovascular disease risk between African American and European American women. The Jackson Heart Study will provide important and unique information relevant to many unanswered questions about obesity, physical inactivity, and obesity in African Americans.
尽管在了解疾病机制和风险因素、改进治疗方法以及开展公众教育方面取得了显著进展，但心血管疾病（CVD）仍是美国的首要死因。肥胖和缺乏身体活动是与生活方式相关的两个重要的心血管疾病风险因素，在美国东南部普遍存在，并且在该国所有种族群体和地区正变得越来越普遍。在审视这些风险因素时，我们探讨了包括人口数据中的患病率和趋势、相关的心理社会和环境因素，以及这些风险因素被认为导致心血管疾病的一些机制等主题。我们发现肥胖、低身体活动水平及其相关因素的患病率存在显著但尚未得到充分理解的种族差异，并研究了非裔美国女性和欧裔美国女性在肥胖、糖尿病与心血管疾病风险之间复杂关系上的重要差异。杰克逊心脏研究将为许多有关非裔美国人肥胖、身体活动不足和肥胖症的未解答问题提供重要且独特的信息。
