Wu Y, Zhou Z, Xiong Y, Wang Y, Sun J
Institute of Chinese Materia Medica, China Academy of Traditional Chinese Medicine, Beijing 100700.
Zhongguo Zhong Yao Za Zhi. 1999 Feb;24(2):84-6, 125.
To assay the aluminum content in alum and some Chinese medicinal herbs processed with alum, and compare the aluminum distribution of these herbs in blood and brain in mice.
Aluminum content of the herbs was assayed with spectrophotometry, snd aluminum distribution in blood and brain was assayed with atomic absorption spectrophotometry.
Aluminum content in alum was found higher than that in the alum-processed herbs. Aluminum distribution in blood and brain after oral administration at equimolecular doses, equivalent to 5.7 mg/kg of metal Al, was studied in mice, and no significant differences were observed.
Aluminum distribution in blood and brain in mice is related to the dosages of aluminum administered and has little to do with the kind of herbs used. All these medicinal herbs do not improve the absorption of aluminum in mice.
测定明矾及一些用明矾炮制的中药材中的铝含量，并比较这些药材在小鼠血液和脑组织中的铝分布情况。
采用分光光度法测定药材中的铝含量，用原子吸收分光光度法测定血液和脑组织中的铝分布。
发现明矾中的铝含量高于用明矾炮制的药材。对小鼠口服等分子剂量（相当于5.7毫克/千克金属铝）后血液和脑组织中的铝分布进行了研究，未观察到显著差异。
小鼠血液和脑组织中的铝分布与铝的给药剂量有关，与所用药材种类关系不大。所有这些中药材均未促进小鼠对铝的吸收。
