Mulaisho C
Med J Zambia. 1979 Oct-Nov;13(5):85-9.
Six male stable insulin dependent diabetics were admitted to the University Teaching Hospital (U.T.H.) to define the insulin regiment that best controls their fasting and 2 hr postprandial blood glucose. Lente and Soluble insulin regiments were evaluated. For this study, blood glucose was estimated in six control subjects and in the six diabetic patients before breakfast lunch and supper and two hours after each of these meals. Each diabetic was allowed three days to stabilise on his usual insulin regimen and for the next three days blood glucose was estimated at the times indicated. Then for the next three days the patient was given the other insulin regimen and then for the last three days and while still on this second regimen blood glucose was estimated at the time indicated. Lente insulin was given as a twice daily dose before breakfast and supper while soluble insulin was administered either as a twice daily dose before breakfast and supper or as a thrice daily dose before breakfast, lunch and supper. The overall control of blood glucose before and two hrs meals was better with soluble insulin regiment than with the Lente insulin regimen.
六名男性稳定型胰岛素依赖型糖尿病患者被收治入大学教学医院（U.T.H.），以确定能最佳控制其空腹及餐后2小时血糖的胰岛素治疗方案。对中效胰岛素和可溶性胰岛素治疗方案进行了评估。在本研究中，对六名对照受试者以及六名糖尿病患者在早餐、午餐和晚餐前及每餐餐后两小时进行血糖测定。每位糖尿病患者先有三天时间以其常用的胰岛素治疗方案稳定病情，在此期间按指定时间测定血糖。接下来的三天，患者使用另一种胰岛素治疗方案，在这三天及之后的三天，患者仍使用第二种治疗方案时，按指定时间测定血糖。中效胰岛素每日早餐前和晚餐前各给药一次，而可溶性胰岛素则每日早餐前和晚餐前各给药一次，或每日早餐前、午餐前和晚餐前各给药一次。可溶性胰岛素治疗方案对血糖的总体控制在餐前及餐后两小时均优于中效胰岛素治疗方案。
